Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website http://www.neurores.org

Original Article

Volume 2, Number 3, June 2012, pages 82-87

Changes in Peripheral Blood Mononuclear Cells-Novel Evidence for an Immunomodulatory Aspect in Bell’s Palsy?

Figure

Figure 1.
Figure 1. a. Percentage of CD14 (monocytes), CD68 (macrophages), CD3 (T-lymphocytes and CD19 (B-lymphocytes) immunoreactive PBMCs in BP patients and healthy subjects. Mean ± SEM; n = 15; P ≤ 0.05 (significance). b. Percentage of double-immunostained CD19 (B-lymphocytes) positive and CD40, TNF-α, COX-2, (proinflammatory markers), PARP and Caspase-3 (proapoptotic markers) or CD38 (adhesion relevant marker) immunoreactive PBMCs in BP patients and healthy subjects (control). Mean ± SEM; n = 15; P ≤ 0.05 (significance). c. Percentage of double-immunostained CD3 (T-lymphocytes) positive and CD40, TNF-α, COX-2, (proinflammatory markers), PARP and Caspase-3 (proapoptotic markers) or CD38 (adhesion relevant marker) immunoreactive PBMCs in BP patients and healthy subjects (control). Mean ±SEM; n = 15; P ≤ 0.05 (significance). d. Percentage of double-immunostained CD68 (macrophages) positive and CD40, TNF-α, COX-2, (proinflammatory markers), PARP and Caspase-3 (proapoptotic markers) or CD38 (adhesion relevant marker) immunoreactive PBMCs in BP patients and healthy subjects (control). Mean ± SEM; n = 15; P ≤ 0.05 (significance). e. Percentage of double-immunostained CD14 (monocytes) positive and CD40, TNF-α, COX-2, (proinflammatory markers), PARP and Caspase-3 (proapoptotic markers) or CD38 (adhesion relevant marker) immunoreactive PBMCs in BP patients and healthy subjects (control). Mean ± SEM; n = 15; P ≤ 0.05 (significance).

Table

Table 1. Age, Blood Lipids, Number of Leukocytes (Including Subpopulations) and PBMC in BPPatients and Healthy Subjects
 
Mean ± SEM; n = 15; P, significance; CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ns, not significant.
ControlBell’s palsyP value
Age (years)48.9 ± 3.2542.8 ± 3.4ns
BMI (kg/m2)27 ± 1.1429.7 ± 0.97ns
Lymphocytes (%)37.43 ± 2.8528.45 ± 2.980.03
Monocytes (%)7.58 ± 0.347.36 ± 0.65ns
Neutrophils (%)52.02 ± 2.6962.42 ± 3.770.03
Eosinophils (%)2.50 ± 0.221.4 ± 0.310.003
Basophils (%)0.47 ± 0.050.35 ± 0.06ns
Leukocytes (109/L)6.95 ± 0.309.04 ± 0.730.008
CRP (mg/dL)1.97 ± 0.294.87 ± 1.330.04