Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc |
Journal website http://www.neurores.org |
Original Article
Volume 2, Number 4, August 2012, pages 127-133
Effects of a PDGFR-a Antagonist Imatinib on Blood-Brain Barrier Disruption in Focal Cerebral Ischemia in Younger and Older Rats
Figures
Table
Group | Younger | Older | ||
---|---|---|---|---|
Control (n = 7) | Imatinib (n = 7) | Control (n = 7) | Imatinib (n = 7) | |
BP: Blood Pressure. Values are means ± SD. | ||||
Systolic BP (mmHg) | 106 ± 16 | 107 ± 23 | 96 ± 13 | 102 ± 36 |
Diastolic BP (mmHg) | 70 ± 11 | 66 ± 15 | 58 ± 11 | 65 ± 25 |
Mean BP (mmHg) | 82 ± 12 | 80 ± 16 | 71 ± 12 | 78 ± 27 |
Heart Rate (beats/min) | 282 ± 39 | 305 ± 52 | 245 ± 57 | 271 ± 39 |
pH | 7.38 ± 0.04 | 7.33 ± 0.10 | 7.34 ± 0.10 | 7.31 ± 0.07 |
PaCO2 (mmHg) | 38 ± 6 | 33 ± 8 | 34 ± 6 | 32 ± 5 |
PaO2 (mmHg) | 122 ± 20 | 118 ± 14 | 105 ± 21 | 107 ± 13 |
Hemoglobin (g/100 mL) | 11.8 ± 1.6 | 11.3 ± 1.4 | 11.4 ± 3.8 | 10.7 ± 2.5 |