Figure 1. Intrathecal immunoglobulin synthesis in the cerebrospinal fluid (CSF): The CSF index for IgA (filled triangles), IgM (filled squares), IgG (filled circles) successively declined during steroid therapy.
Figure 2. Axial Cranial MRI: Susceptibility Weighted Imaging (SWI) MRI displays multifocal black dots localized in the left parietooccipital lobe (A). Fluid Attenuated Inversion Recovery (FLAIR) MRI shows multiple white matter lesions particularly in the left parietooccipital area with an extensive edema and significant mass effect (B).
Figure 3. Brain biopsy (left occipital lobe): A medium sized vessel with granulomatous inflammatory infiltrate, deposition of amyloid-β in vessel wall (A, immunohistochemical staining against amyloid-β, arrow) and multinucleated macrophages (B, immunohistochemical staining with the macrophage marker CD68, arrow).