Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc |
Journal website http://www.neurores.org |
Original Article
Volume 6, Number 2-3, June 2016, pages 46-50
Insulin Resistance as an Inflammatory Marker for Ischemic Stroke Severity Among Non-Diabetics: A Prospective Study
Table
Parameter | Category | NIHSS at admission | |||
---|---|---|---|---|---|
Group I (1 - 8) | Group II (9 - 18) | Group III (> 18) | P value | ||
BMI: basal metabolic index; WC: waist circumference; HTN: hypertension; T.CHO: total cholesterol; LDL: low density cholesterol; TGL: triglycerides; FBS: fasting blood sugar; HbA1c: glycated hemoglobin; HOMA-IR: homeostatic method assessment insulin resistance; NIHSS: National Institutes of Health Sciences Scale. | |||||
Gender | M (%) | 45 (72.6%) | 55 (70.5%) | 16 (72.7%) | 0.95 |
F (%) | 17 (27.4%) | 23 (29.5%) | 6 (27.3%) | ||
40 - 49 years | 19 (30.6%) | 15 (19.2 %) | 2 (9.1%) | ||
50 - 59 years | 22 (35.5%) | 27 (34.6%) | 8 (36.4%) | ||
60 - 69 years | 12 (19.4%) | 18 (23.1%) | 7 (31.8%) | ||
> 70 years | 4 (6.5% ) | 12 (15.4%) | 3 (13.6 %) | ||
BMI (kg/m2) | < 23 | 8 (12.9%) | 17 (21.8%) | 5 (22.7%) | 0.34 |
≥ 23 | 54 (87.1%) | 61 (78.2%) | 17 (77.3%) | ||
WC (cm) | M < 90 | 20 (37.7%) | 22 (41.5%) | 11 (20.8%) | 0.12 |
M ≥ 90 | 25 (39.7%) | 33 (52.4%) | 5 (7.9%) | ||
F < 80 | 7 (46.7%) | 7 (46.7%) | 1 (6.7%) | 0.51 | |
F ≥ 80 | 10 (32.3%) | 16 (51.6%) | 5 (16.1%) | ||
HTN | Yes (%) | 34 (54.8%) | 50 (64.1 %) | 14 (63.6%) | 0.51 |
No (%) | 28 (45.2 %) | 28 (35.9 %) | 8 (36.4 %) | ||
No (%) | 36 (58.8 %) | 48 (61.5 %) | 14 (63.6 %) | ||
T.CHO (mg/dL) | < 200 | 40 (64.5 %) | 46 (59.0 %) | 12 (54.5 %) | 0.66 |
≥ 200 | 22 (35.5 %) | 32 (41.0 %) | 10 (45.5 %) | ||
LDL (mg/dL) | ≤ 100 | 24 (38.7%) | 21 (26.9%) | 11 (50.0%) | 0.09 |
> 100 | 38 (61.3%) | 57 (73.1 %) | 11 (50.0%) | ||
TGL (mg/dL) | < 150 | 25 (40.3%) | 30 (38.5%) | 12 (54.5%) | 0.39 |
≥ 150 | 37 (59.7%) | 48 (61.5%) | 10 (45.5%) | ||
FBS (mg/dL) | ≤ 100 | 48 (77.4%) | 50 (64.1%) | 13 (59.1%) | 0.14 |
101 - 125 | 14 (22.6%) | 28 (35.9%) | 9 (40.9 %) | ||
HbA1C | ≤ 5.6 | 37 (59.7%) | 46 (59.0%) | 12 (54.5%) | 0.91 |
5.7 - 6.4 | 25 (40.3%) | 32 (41.0%) | 10 (45.5%) | ||
S. insulin | ≤ 9 | 51 (82.3%) | 60 (76.9%) | 10 (45.5%) | 0.002 |
> 9 | 11 (17.7%) | 18 (23.1%) | 12 (54.5%) | ||
HOMA-IR | < 1.0 | 15 (24.2%) | 22 (28.2% ) | 1 (4.5%) | < 0.0001 |
1 - 1.5 | 16 (25.8%) | 13 (16.7%) | 3 (13.6%) | ||
1.5 - 2.0 | 14 (22.6%) | 7 (9.0%) | 1 (4.5%) | ||
2.0 - 2.5 | 10 (16.1%) | 7 (9.0%) | 5 (22.7%) | ||
≥ 2.5 | 7 (11.3%) | 12 (15.4%) | 12 (54.5%) |