Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website http://www.neurores.org

Original Article

Volume 6, Number 2-3, June 2016, pages 46-50


Insulin Resistance as an Inflammatory Marker for Ischemic Stroke Severity Among Non-Diabetics: A Prospective Study

Table

Table 1. Comparison of Demographic, Anthropometric and Biochemical Parameters in Relation to Stroke Severity
 
ParameterCategoryNIHSS at admission
Group I (1 - 8)Group II (9 - 18)Group III (> 18)P value
BMI: basal metabolic index; WC: waist circumference; HTN: hypertension; T.CHO: total cholesterol; LDL: low density cholesterol; TGL: triglycerides; FBS: fasting blood sugar; HbA1c: glycated hemoglobin; HOMA-IR: homeostatic method assessment insulin resistance; NIHSS: National Institutes of Health Sciences Scale.
GenderM (%)45 (72.6%)55 (70.5%)16 (72.7%)0.95
F (%)17 (27.4%)23 (29.5%)6 (27.3%)
40 - 49 years19 (30.6%)15 (19.2 %)2 (9.1%)
50 - 59 years22 (35.5%)27 (34.6%)8 (36.4%)
60 - 69 years12 (19.4%)18 (23.1%)7 (31.8%)
> 70 years4 (6.5% )12 (15.4%)3 (13.6 %)
BMI (kg/m2)< 238 (12.9%)17 (21.8%)5 (22.7%)0.34
≥ 2354 (87.1%)61 (78.2%)17 (77.3%)
WC (cm)M < 9020 (37.7%)22 (41.5%)11 (20.8%)0.12
M ≥ 9025 (39.7%)33 (52.4%)5 (7.9%)
F < 807 (46.7%)7 (46.7%)1 (6.7%)0.51
F ≥ 8010 (32.3%)16 (51.6%)5 (16.1%)
HTNYes (%)34 (54.8%)50 (64.1 %)14 (63.6%)0.51
No (%)28 (45.2 %)28 (35.9 %)8 (36.4 %)
No (%)36 (58.8 %)48 (61.5 %)14 (63.6 %)
T.CHO (mg/dL)< 20040 (64.5 %)46 (59.0 %)12 (54.5 %)0.66
≥ 20022 (35.5 %)32 (41.0 %)10 (45.5 %)
LDL (mg/dL)≤ 10024 (38.7%)21 (26.9%)11 (50.0%)0.09
> 10038 (61.3%)57 (73.1 %)11 (50.0%)
TGL (mg/dL)< 15025 (40.3%)30 (38.5%)12 (54.5%)0.39
≥ 15037 (59.7%)48 (61.5%)10 (45.5%)
FBS (mg/dL)≤ 10048 (77.4%)50 (64.1%)13 (59.1%)0.14
101 - 12514 (22.6%)28 (35.9%)9 (40.9 %)
HbA1C≤ 5.637 (59.7%)46 (59.0%)12 (54.5%)0.91
5.7 - 6.425 (40.3%)32 (41.0%)10 (45.5%)
S. insulin≤ 951 (82.3%)60 (76.9%)10 (45.5%)0.002
> 911 (17.7%)18 (23.1%)12 (54.5%)
HOMA-IR< 1.015 (24.2%)22 (28.2% )1 (4.5%)< 0.0001
1 - 1.516 (25.8%)13 (16.7%)3 (13.6%)
1.5 - 2.014 (22.6%)7 (9.0%)1 (4.5%)
2.0 - 2.510 (16.1%)7 (9.0%)5 (22.7%)
≥ 2.57 (11.3%)12 (15.4%)12 (54.5%)