J Neurol Res

Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc

Journal website http://www.neurores.org

Original Article

Volume 6, Number 5-6, December 2016, pages 95-101

A Study on Clinico-Biochemical Profile of Neonatal Seizure

Figure 5. Distribution of patients of non-metabolic seizure in accordance with biochemical profile.

**Table 1.** Distribution of Gender and Place of Delivery of Babies With Neonatal Seizures
Sex-wise distribution of neonatal seizures	n = 115 (100%)
Male, n (%)	72 (62.6 %)
Female, n (%)	43 (37.4%)
Place of delivery of babies with neonatal seizures	n = 115 (100%)
Home delivery, n (%)	2 (1.7%)
Hospital delivery, n (%)	113 (98.3%)

Table 1. Distribution of Gender and Place of Delivery of Babies With Neonatal Seizures

Sex-wise distribution of neonatal seizures

n = 115 (100%)

Male, n (%)

72 (62.6 %)

Female, n (%)

43 (37.4%)

Place of delivery of babies with neonatal seizures

n = 115 (100%)

Home delivery, n (%)

2 (1.7%)

Hospital delivery, n (%)

113 (98.3%)

**Table 2.** Birth Weight of Babies With Seizures
Birth weight (kg)	No. (%)
> 2.5	75 (65.2%)
2 - 2.5	29 (25.2%)
1 - 2	11 (9.6%)
< 1	-
Total	115 (100%)

Table 2. Birth Weight of Babies With Seizures

Birth weight (kg)

No. (%)

> 2.5

75 (65.2%)

2 - 2.5

29 (25.2%)

1 - 2

11 (9.6%)

< 1

Total

115 (100%)

**Table 3.** Type of Seizures
Type of seizures	No. (%)
Subtle	49 (42.6%)
Generalized tonic	39 (33.9%)
Multifocal clonic	10 (8.7%)
Focal clonic	8 (7%)
Subtle with GTS	6 (5.2%)
Subtle with clonic	3 (2.6%)
Total	115 (100%)

Table 3. Type of Seizures

Type of seizures

No. (%)

Subtle

49 (42.6%)

Generalized tonic

39 (33.9%)

Multifocal clonic

10 (8.7%)

Focal clonic

8 (7%)

Subtle with GTS

6 (5.2%)

Subtle with clonic

3 (2.6%)

Total

115 (100%)

**Table 4.** Overall Biochemical Profile in Patients With Neonatal Seizures
Seizures	Biochemical abnormalities	Total
Non-metabolic seizures	-	4 (10%)	6 (15%)	1 (2.5%)	26 (65%)	1 (2.5%)	2 (5%)	40 (100%)
Metabolic seizures	-	2 (15.4%)	1 (7.6%)	1 (7.6%)	-	-	9 (69.2%)	13 (100%)
Total	-	6 (11.32%)	7 (13.2%)	2 (3.77%)	26 (49%)	1 (1.8%)	11 (20.75%)	53 (100%)

Table 4. Overall Biochemical Profile in Patients With Neonatal Seizures

Seizures

Biochemical abnormalities

Total

Hypocalcemia

Hypomagnesemia

Hypermagnesemia

Hypocalcemia + hypomagnesemia

Hypocalcemia

Hypercalcemia

Hypoglycemia

Non-metabolic seizures

4 (10%)

6 (15%)

1 (2.5%)

26 (65%)

1 (2.5%)

2 (5%)

40 (100%)

Metabolic seizures

2 (15.4%)

1 (7.6%)

9 (69.2%)

13 (100%)

Total

6 (11.32%)

7 (13.2%)

2 (3.77%)

26 (49%)

1 (1.8%)

11 (20.75%)

53 (100%)

**Table 5.** Distribution of Neonate Having Metabolic Seizure in Accordance With Biochemical Profile
Gestational age	Biochemical abnormalities	Total
Pre-term	-	0	1 (20%)	-	4 (80%)	5 (100%)
Term AGA	-	1 (33.3%)	-	1 (33.3%)	1 (33.3%)	3 (100%)
Term SGA	-	-	1 (20%)	-	4 (80%)	5 (100%)
Total	-	1 (7.7%)	2 (15.45%)	1 (7.7%)	9 (69.2%)	13 (100%)

Table 5. Distribution of Neonate Having Metabolic Seizure in Accordance With Biochemical Profile

Gestational age

Biochemical abnormalities

Total

Hypocalcemia

Hypermagnesemia

Hypomagnesemia

Hypocalcemia + hypomagnesemia

Hypoglycemia

Pre-term

1 (20%)

4 (80%)

5 (100%)

Term AGA

1 (33.3%)

3 (100%)

Term SGA

1 (20%)

4 (80%)

5 (100%)

Total

1 (7.7%)

2 (15.45%)

1 (7.7%)

9 (69.2%)

13 (100%)

**Table 6.** Levels of Magnesium and Combined Hypocalcemia and Hypomagnesemia in Metabolic and Non-Metabolic Seizures
	Biochemical profile	Total
Non-metabolic	4 (40%)	5 (50%)	1 (10%)	10 (100%)
Metabolic	2 (50%)	1 (25%)	1 (25%)	4 (100%)
Total	6 (42.9%)	6 (42.9%)	2 (14.3%)	14 (100%)

Table 6. Levels of Magnesium and Combined Hypocalcemia and Hypomagnesemia in Metabolic and Non-Metabolic Seizures

Biochemical profile

Total

Hypomagnesemia

Hypermagnesemia

Hypocalcemia + hypomagnesemia

Non-metabolic

4 (40%)

5 (50%)

1 (10%)

10 (100%)

Metabolic

2 (50%)

1 (25%)

4 (100%)

Total

6 (42.9%)

2 (14.3%)

14 (100%)