Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website http://www.neurores.org

Original Article

Volume 9, Number 3, June 2019, pages 28-34

Repetitive Transcranial Magnetic Stimulation in Treatment of Levodopa-Induced Dyskinesia in Parkinson’s Disease

Figure

Figure 1.
Figure 1. MagPro R30 magnetic stimulator (MagVenture, Farum, Denmark, 2012).

Tables

Table 1. Comparison Between Demographic Data of the Study and Control Group Patients Before rTMS
 
DataStudy group (n = 20)Control group (n = 20)P
This table shows no statistical difference between both groups regarding age, sex and duration of illness.
Age66.65 ± 4.5866.60 ± 5.97t = 0.0300.976
SexNo%No%
  Men945%1260%χ2 = 0.9020.342
  Women1155%840%
Duration of illness68.10 ± 5.3568.75 ± 5.30t = 0.3860.702

 

Table 2. Comparison Between Both Groups as Regards to the Disease Staging Before rTMS
 
Stage of Parkinson’s diseaseStudy groupControl groupχ2P
No%No%
III735%945%0.4720.790
IV1050%840%
V315%315%

 

Table 3. The Comparison Between Clinical Presentations of LID in Study and Control Groups Before rTMS
 
DyskinesiaStudy group (n = 20)Control group (n = 20)tP
Dyskinesia duration (% of the day)0.95 ± 1.050.85 ± 1.040.3030.764
Dyskinesia disability1.05 ± 1.280.90 ± 1.290.3690.714
Painful dyskinesia0.50 ± 0.690.60 ± 0.820.4180.679
Early morning dystonia0.35 ± 0.490.50 ± 0.610.8600.395

 

Table 4. Comparison Between Individual Clinical Presentations of LID in Study and Control Groups After rTMS
 
DyskinesiaStudy group (n = 20)Control group (n = 20)tP
*Statistically significant P < 0.05.
Dyskinesia duration (% of the day)0.50 ± 0.890.85 ± 0.991.1780.246
Dyskinesia disability0.60 ± 1.140.90 ± 1.210.8060.425
Painful dyskinesia0.20 ± 0.410.60 ± 0.752.0840.046*
Early morning dystonia0.20 ± 0.410.55 ± 0.691.9570.059

 

Table 5. Comparison Between Dyskinesia Before and After rTMS in Each Group
 
PtDyskinesiaGroup
After stimulationBefore stimulation
*Statistically significant P < 0.05.
< 0.001*5.7297.35 ± 6.8211.15 ± 7.65Study group
0.5850.55610.85 ± 7.4011.05 ± 7.57Control group