Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website http://www.neurores.org

Original Article

Volume 9, Number 4-5, October 2019, pages 60-64

Update on an Asian Indian Family With Apparent Autosomal Recessive Charcot-Marie-Tooth Disease Caused by a Mutation in the HSPB1 Gene

Figures

Figure 1.
Figure 1. Pedigree of the family with adult-onset Charcot-Marie-Tooth disease. The squares indicate males, circles indicate females, and dark fill indicates symptomatic individuals. The black dot indicates individuals with the deletion mutation in PRX gene and the black star indicates individuals carrying HSPB1 gene variant. The number below the symbols represents the approximate age of onset of affected individuals.
Figure 2.
Figure 2. Genotyping analysis of the HSPB1 (a) and PRX (b) genes in this family. PCR products are resolved on a 4% agarose gel. PCR: polymerase chain reaction.