Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website https://www.neurores.org

Original Article

Volume 12, Number 3, October 2022, pages 114-120

A Novel Radiographic and Clinical Assessment Scoring Tool for Seizure Risk Stratification in the Acute Phase of Cerebral Venous Sinus Thrombosis: A Systematic Review and Meta-Analysis

Figure

Figure 1.
Figure 1. Flow diagram of search process and study selection.

Tables

Table 1. Odds Ratio (OR) Calculated by the Random-Effects Model for Seizure Occurrence Between Cerebral Venous Thrombosis Patients With and Without Each Risk Factor Studied
 
OR95% CI
CI: confidence interval.
Location
  Frontal lobe4.853.52 - 6.68
  Parietal lobe2.521.41 - 4.52
  Temporal lobe1.580.60 - 4.14
  Occipital lobe0.990.62 - 1.59
Sinus type
  Superficial sagittal sinus1.971.17 - 3.30
  Cortical vein3.162.18 - 4.58
  Transverse (lateral) sinus0.600.50 - 0.73
  Straight sinus0.630.40 - 0.90
  Sigmoid sinus1.110.74 -1.66
  Deep cerebral vein0.390.07 - 2.07
Venous ischemia type
  Hemorrhagic3.853.20 - 4.64
  Non-hemorrhagic1.491.13 - 1.98
Symptom or sign
  Headache0.350.18 - 0.66
  Confusion2.151.57 - 2.94
  Aphasia1.180.47 - 2.95
  Motor deficit3.072.66 - 3.55
  Papilledema0.360.22 - 0.58
  Sensory disturbance1.730.45- 6.67
  Nausea/vomiting0.770.58 - 1.03

 

Table 2. A Novel Radiographic and Clinical Assessment (RC) Scoring System
 
Risk factorsScore
Radiographic finding (R)
  Frontal lobe1.5
  Parietal lobe0.5
  Cortical veins1
  Hemorrhagic venous ischemia1.5
Clinical presentation (C)
  Motor deficit0.5
  Confusion1

 

Table 3. Score Interpretation for the Radiographic and Clinical assessment (RC) Scoring System
 
RC scoreEstimated seizure risk (%)
040
148
252
360
468
580
692