Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website https://www.neurores.org

Original Article

Volume 13, Number 1, September 2023, pages 43-49

The Clinical Spectrum of Multiple Sclerosis in a Tertiary Care Hospital

Figures

Figure 1.
Figure 1. Relapsing-remitting multiple sclerosis (RRMS), secondary-progressive multiple sclerosis (SPMS), and primary-progressive multiple sclerosis (PPMS) are each represented in a bar diagram with respect to the relative frequency of oligoclonal bands (OCBs) positive status.
Figure 2.
Figure 2. A bar graph comparing the proportional frequency of the visual evoked potentials (VEPs) positive status to the frequency of positive clinical visual symptoms.
Figure 3.
Figure 3. MRI of brain T2 sequence axial section showing periventricular deep white matter lesions (as shown by the arrows in the sequence labeled as 1). MRI of brain T2 sequence coronal section in the corresponding regions shows an abnormal hyperintense signal (as shown by the arrows in the sequence labeled as 2). MRI of brain post-contrast T1 sequence in the corresponding regions shows a hypointense signal (as shown by the arrows in the sequence labeled as 3). MRI of the cervical spine sagittal section shows short segment abnormal cord hyperintensity (as shown by the arrows in the sequence labeled as 4). These images correspond to a 24-year-old woman who presented with right-hand monoplegia. She also had a recent history of sudden onset decreased vision in the right eye which has subsided spontaneously. MRI: magnetic resonance imaging.
Figure 4.
Figure 4. MRI of brain T2 sagittal sequence showing three periventricular lesions (as shown by the arrows in the sequence labeled 1). MRI of cervical spine T2 sagittal sequence showing short segment hyperintensity (as shown by the arrows in the sequence labeled 2). MRI of cervical spine T1 post-contrast sagittal sequence showing contrast enhancement in the corresponding region (as shown by arrows in the sequence labeled 3) in a 28-year-old woman with a 10-day history of pain and paraesthesia in the occipital and neck region. MRI: magnetic resonance imaging.

Tables

Table 1. Demographic and Clinical Features of Study Subjects
 
Characteristics
Values are shown as numbers with percentages in parentheses. MS: multiple sclerosis; RR: relapsing-remitting; SP: secondary-progressive; PP: primary-progressive; SD: standard deviation.
Total20
Males (%)4 (20)
Females (%)16 (80)
Female/male4:1
Age in years (mean ± SD)27 ± 12
Range of age in years 18 - 48 (onset)10 - 52
Disease course
  RRMS (%)16 (80%)
  PPMS (%)3 (15%)
  SPMS (%)1 (5%)

 

Table 2. MRI Characteristics
 
MRI MS protocol characteristics< 4 T2 lesions4 - 8 T2 lesions≥ 9 T2 lesionsGadolinium enhancementInfratentorial lesions
MRI: magnetic resonance imaging; MS: multiple sclerosis; T2: T2 sequence of MRI.
First MRI659911
Second MRI2711916