Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc |
Journal website https://www.neurores.org |
Original Article
Volume 13, Number 1, September 2023, pages 50-55
Measurement of Electrophysiology, Sexual Dysfunction, and Cognitive Impairment in Patients With Diabetes Referred for Neuropathy Symptoms: A Case-Control Study
Tables
Variables | Neuropathy diabetes (n = 110) | Non-diabetic controls (n = 52) | P value |
---|---|---|---|
Data were expressed as n (%) or mean ± standard deviation. IHD: ischemic heart disease; BMI: body mass index; MoCA: Montreal cognitive assessment; FSFI: female sexual function index, MSFI: male sexual function index. | |||
Sex | |||
Male/female, n (%) | 57 (51.8)/53 (48.2) | 20 (38.5)/32 (61.5) | 0.112 |
Comorbidity | |||
Hypertension, n (%) | 53 (48.6) | 8 (15.4) | 0.001 |
IHD, n (%) | 23 (21.1) | 2 (3.8) | 0.001 |
Age | 57.96 ± 9.75 | 55.57 ± 10.53 | 0.158 |
BMI (kg/m2) | 31.2 ± 5.4 | 30.1 ± 6.2 | 0.2 |
Duration of disease | 10.51 ± 7.17 | - | - |
Beck score | 8.56 ± 6.47 | 8.96 ± 4.74 | 0.451 |
MoCA | 20.98 ± 5.07 | 23.17 ± 4.47 | 0.001 |
Sexual activity | |||
FSFI | 11.03 ± 8.13 | 14.05 ± 9.46 | 0.122 |
Desire | 3.23 ± 1.32 | 3.05 ± 1.44 | 0.438 |
Arousal | 2.27 ± 2.02 | 2.86 ± 2.30 | 0.119 |
Lubrication | 1.19 ± 1.27 | 1.47 ± 1.34 | 0.341 |
Orgasm | 1.76 ± 1.75 | 2.15 ± 1.85 | 0.338 |
Satisfaction | 2.23 ± 1.84 | 2.36 ± 1.87 | 0.667 |
Pain | 1.23 ± 1.57 | 1.41 ± 1.50 | 0.609 |
MSFI | 15.10 ± 8.05 | 17.2 ± 12.5 | 0.395 |
Desire | 3.23 ± 1.23 | 3.05 ± 1.44 | 0.438 |
Arousal | 2.27 ± 2.02 | 2.86 ± 2.30 | 0.119 |
Erection | 1.96 ± 1.68 | 1.75 ± 1.68 | 0.636 |
Orgasm | 2.23 ± 1.84 | 2.36 ± 1.87 | 0.667 |
Satisfaction | 3.17 ± 2.26 | 3.60 ± 2.36 | 0.275 |
Variables | Patients | Non-diabetic controls | P value* |
---|---|---|---|
Data are expressed as mean ± standard deviation. *P < 0.05. NCS: nerve conduction study; NSS: neuropathy symptom score; NDS: neuropathy disability score; SRAR: sural/radial nerve amplitude ratio; CMAP: compound muscle action potential. | |||
NSS | 5.83 ± 2.40 | 1.72 ± 1.96 | 0.001 |
NDS | 4.11 ± 2.45 | 0.43 ± 1.02 | 0.001 |
SRAR | 0.27 ± 0.19 | 0.56 ± 0.1 | 0.001 |
Mean tibial conduction velocity | 35.00 ± 16.04 | 44.75 ± 3.55 | 0.001 |
Mean tibial distal latency | 5.12 ± 0.92 | 4.42 ± 0.68 | 0.001 |
Mean tibial CMAP amplitude | 10.32 ± 14.89 | 5.34 ± 1.84 | 0.001 |
Mean sural amplitude | 6.75 ± 5.75 | 15.32 ± 4.5 | 0.001 |
Mean radial sensory amplitude | 20.82 ± 8.35 | 27.02 ± 7.33 | 0.001 |
SRAR | ||||||
---|---|---|---|---|---|---|
Total | Patients | Comparison | ||||
r | P* | r | P* | r | P* | |
*P < 0.05. NSS: neuropathy symptom score; NDS: neuropathy disability score; SRAR: sural/radial nerve amplitude ratio. | ||||||
NSS | -0.848 | 0.001 | -0.811 | 0.001 | -0.398 | 0.012 |
NDS | -0.856 | 0.001 | -0.795 | 0.001 | -0.44 | 0.005 |