Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website https://www.neurores.org

Original Article

Volume 13, Number 1, September 2023, pages 50-55


Measurement of Electrophysiology, Sexual Dysfunction, and Cognitive Impairment in Patients With Diabetes Referred for Neuropathy Symptoms: A Case-Control Study

Tables

Table 1. Clinical Features of Study Participation
 
VariablesNeuropathy diabetes (n = 110)Non-diabetic controls (n = 52)P value
Data were expressed as n (%) or mean ± standard deviation. IHD: ischemic heart disease; BMI: body mass index; MoCA: Montreal cognitive assessment; FSFI: female sexual function index, MSFI: male sexual function index.
Sex
  Male/female, n (%)57 (51.8)/53 (48.2)20 (38.5)/32 (61.5)0.112
Comorbidity
  Hypertension, n (%)53 (48.6)8 (15.4)0.001
  IHD, n (%)23 (21.1)2 (3.8)0.001
Age57.96 ± 9.7555.57 ± 10.530.158
BMI (kg/m2)31.2 ± 5.430.1 ± 6.20.2
Duration of disease10.51 ± 7.17--
Beck score8.56 ± 6.478.96 ± 4.740.451
MoCA20.98 ± 5.0723.17 ± 4.470.001
Sexual activity
  FSFI11.03 ± 8.1314.05 ± 9.460.122
    Desire3.23 ± 1.323.05 ± 1.440.438
    Arousal2.27 ± 2.022.86 ± 2.300.119
    Lubrication1.19 ± 1.271.47 ± 1.340.341
    Orgasm1.76 ± 1.752.15 ± 1.850.338
    Satisfaction2.23 ± 1.842.36 ± 1.870.667
    Pain1.23 ± 1.571.41 ± 1.500.609
  MSFI15.10 ± 8.0517.2 ± 12.50.395
    Desire3.23 ± 1.233.05 ± 1.440.438
    Arousal2.27 ± 2.022.86 ± 2.300.119
    Erection1.96 ± 1.681.75 ± 1.680.636
    Orgasm2.23 ± 1.842.36 ± 1.870.667
    Satisfaction3.17 ± 2.263.60 ± 2.360.275

 

Table 2. NCS Parameters
 
VariablesPatientsNon-diabetic controlsP value*
Data are expressed as mean ± standard deviation. *P < 0.05. NCS: nerve conduction study; NSS: neuropathy symptom score; NDS: neuropathy disability score; SRAR: sural/radial nerve amplitude ratio; CMAP: compound muscle action potential.
NSS5.83 ± 2.401.72 ± 1.960.001
NDS4.11 ± 2.450.43 ± 1.020.001
SRAR0.27 ± 0.190.56 ± 0.10.001
Mean tibial conduction velocity35.00 ± 16.0444.75 ± 3.550.001
Mean tibial distal latency5.12 ± 0.924.42 ± 0.680.001
Mean tibial CMAP amplitude10.32 ± 14.895.34 ± 1.840.001
Mean sural amplitude6.75 ± 5.7515.32 ± 4.50.001
Mean radial sensory amplitude20.82 ± 8.3527.02 ± 7.330.001

 

Table 3. Correlation Between SRAR and NSS and NDS
 
SRAR
TotalPatientsComparison
rP*rP*rP*
*P < 0.05. NSS: neuropathy symptom score; NDS: neuropathy disability score; SRAR: sural/radial nerve amplitude ratio.
NSS-0.8480.001-0.8110.001-0.3980.012
NDS-0.8560.001-0.7950.001-0.440.005