J Neurol Res

Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc

Journal website https://www.neurores.org

Original Article

Volume 14, Number 1, June 2024, pages 1-7

Small Number of Coils With Extended Length in the Endovascular Treatment of Cerebral Aneurysm: Experience of 108 Cases in a Single-Center

Figure 2. Case illustration of aneurysmal SAH of a 66-year-old female who underwent simple endovascular coiling. CT scan revealed a diffuse SAH (a). DSA showed a saccular cerebral aneurysm located in ACoA with neck 1.07 mm, dome 3.88 × 2.55 mm (arrow) (b). The first coil (4 mm × 10 cm framing coil) was inserted (c), followed by the second coil (3 mm × 10 cm helical coil) (arrow). Packing density was achieved by 30.53% (arrow) (d). ACoA: anterior communicating artery; CT: computed tomography; DSA: digital subtraction angiography; SAH: subarachnoid hemorrhage.

**Table 1.** Clinical Characteristics of Patients
Variables	n	%
Age (years)
< 40	12	11
40 - 49	29	27
50 - 59	37	34
60 - 69	20	19
≥ 70	10	9
Gender
Female	67	62
Male	41	38
Risk factors
Hypertension	84	78
Diabetes mellitus	17	16
Dyslipidemia	37	34
Smoking/former	16	15
Family history	7	6
Aneurysms status
Ruptured	98	84
Unruptured	18	16
In-hospital mortality
Survive	92	85
Not survive	16	15
Aneurysms size
< 5 mm	66	57
5 - 10 mm	42	36
> 10 mm	8	7

Table 1. Clinical Characteristics of Patients

Variables

Age (years)

< 40

40 - 49

50 - 59

60 - 69

≥ 70

Gender

Female

Male

Risk factors

Hypertension

Diabetes mellitus

Dyslipidemia

Smoking/former

Family history

Aneurysms status

Ruptured

Unruptured

In-hospital mortality

Survive

Not survive

Aneurysms size

< 5 mm

5 - 10 mm

> 10 mm

**Table 2.** Location and Size of Aneurysms
Location	Size
ACA: anterior cerebral artery; ACoA: anterior communicating artery; MCA: middle cerebral artery; PCA: posterior cerebral artery; PCoA: posterior communicating artery; SCA: superior cerebral artery.
Anterior
ACA	3 (4.54%)	2 (4.76%)	0 (0%)
MCA	9 (13.64%)	7 (16.67%)	1 (12.50%)
ACoA	27 (40.90%)	10 (23.81%)	2 (25.00%)
Carotid	12 (18.18%)	8 (19.05%)	3 (37.50%)
Opthalmic	1 (1.52%)	0 (0%)	0 (0%)
Posterior
PCoA	10 (15.15%)	13 (30.95%)	2 (25.00%)
PCA	1 (1.52%)	0 (0%)	0 (0%)
SCA	1 (1.52%)	0 (0%)	0 (0%)
Vertebral	2 (3.03%)	2 (4.76%)	0 (0%)

Table 2. Location and Size of Aneurysms

Location

Size

< 5 mm (n = 66)

5 - 10 mm (n = 42)

> 10 mm (n = 8)

ACA: anterior cerebral artery; ACoA: anterior communicating artery; MCA: middle cerebral artery; PCA: posterior cerebral artery; PCoA: posterior communicating artery; SCA: superior cerebral artery.

ACA

3 (4.54%)

2 (4.76%)

0 (0%)

MCA

9 (13.64%)

7 (16.67%)

1 (12.50%)

ACoA

27 (40.90%)

10 (23.81%)

2 (25.00%)

Carotid

12 (18.18%)

8 (19.05%)

3 (37.50%)

Opthalmic

1 (1.52%)

0 (0%)

Posterior

PCoA

10 (15.15%)

13 (30.95%)

2 (25.00%)

PCA

1 (1.52%)

0 (0%)

SCA

1 (1.52%)

0 (0%)

Vertebral

2 (3.03%)

2 (4.76%)

0 (0%)

**Table 3.** Characteristic Features of Coils and Size of Aneurysms
Coil features	Size	P-value
SD: standard deviation.
Framing coil
Number, mean ± SD	0.86 ± 0.55	0.97 ± 1.5	1.12 ± 1.64	0.799
Diameter size, mean ± SD	3.19 ± 1.01 mm	4.64 ± 1.79 mm	9.67 ± 3.46 mm	0.015
Length, ± SD	6.76 ± 4.14 cm	11.28 ± 6.93 cm	29.33 ± 12.59 cm	< 0.001
Helical coil
Number, mean ± SD	1.5 ± 0.94	2.52 ± 0.81	2.75 ± 1.9	< 0.001
Diameter size, mean ± SD	2.69 ± 1.03 mm	4.17 ± 1.94 mm	7.0 ± 3.16 mm	< 0.001
Length, ± SD	5.95 ± 2.82 cm	11.66 ± 7.3 cm	22.32 ± 11.48 cm	< 0.001
Packing density, mean ± SD	46.70±3.15%	33.06±0.26%	35.46±0.31%	< 0.001

Table 3. Characteristic Features of Coils and Size of Aneurysms

Coil features

Size

P-value

< 5 mm (n = 66)

5 - 10 mm (n = 42)

> 10 mm (n = 8)

SD: standard deviation.

Framing coil

Number, mean ± SD

0.86 ± 0.55

0.97 ± 1.5

1.12 ± 1.64

0.799

Diameter size, mean ± SD

3.19 ± 1.01 mm

4.64 ± 1.79 mm

9.67 ± 3.46 mm

0.015

Length, ± SD

6.76 ± 4.14 cm

11.28 ± 6.93 cm

29.33 ± 12.59 cm

< 0.001

Helical coil

Number, mean ± SD

1.5 ± 0.94

2.52 ± 0.81

2.75 ± 1.9

< 0.001

Diameter size, mean ± SD

2.69 ± 1.03 mm

4.17 ± 1.94 mm

7.0 ± 3.16 mm

< 0.001

Length, ± SD

5.95 ± 2.82 cm

11.66 ± 7.3 cm

22.32 ± 11.48 cm

< 0.001

Packing density, mean ± SD

46.70±3.15%

33.06±0.26%

35.46±0.31%

< 0.001