Acute Disseminated Encephalopathy Combined With Anticentromere Antibody B Positive: Uncommon Primary Manifestations of Sjogren’s Syndrome

Abstract

Sjogren’s syndrome (SS) can involve the central nervous system; however, acute disseminated encephalopathy has rarely been reported as the initial manifestation. We report a 60-year-old woman with SS and anticentromere antibody B positive, presenting with acute disseminated encephalopathy. The diagnosis of SS was based on the presence of ocular staining score and labial salivary gland biopsies. SS can present with variable central nervous system signs and anticentromere antibody B positive, which may precede the classic sicca symptoms. Therefore, earlier recognition and treatment for this situation is important.




J Neurol Res. 2016;6(2-3):51-54
doi: http://dx.doi.org/10.14740/jnr376e