Comparative Study of the Prognosis of Ischemic Cerebral Stroke Subtypes

Abstract

Background: The aim of the study was to search if prognosis of ischemic cerebral stroke is affected by its subtypes with regard to its etiology, anatomical site, radiological size, and clinical severity.

Methods: This study was conducted on 43 patients of both sexes with ischemic cerebral stroke admitted to the Neurology Department of Menoufia University Hospitals. Their ages were ranging from 48 to 72 years old and the mean age of cases was 61.26 ± 5.37, while in controls was 58.50 ± 4.70. Clinical severity of stroke was assessed using National Institutes of Health Stroke Scale (NIHSS). The etiological subtypes of stroke were classified according to Trial of Organization 10172 in Acute Stroke Treatment classification. The anatomical site of stroke was evaluated by using the Oxford Community Stroke Project classification. Its size was measured by neuroimaging. Favorable outcome (FO) was defined as modified Rankin scale (0 - 2) while unfavorable outcome (UO) was defined as modified Rankin scale (3 - 6) after 3 months of onset of the stroke.

Results: The UO was correlated with the large vessel stroke (P < 0.001), severe and very severe NIHH scores (P < 0.047 and P < 0.041, respectively), total anterior circulation stroke (P < 0.001), and lesion size > 3 mm (P = 0.007). The FO was correlated with small vessel disease (P < 0.001), mild NIHSS score (P ≤ 0.0001), lacunar infarction (P < 0.001), and infarct size < 1.5 mm (P = 0.001).

Conclusion: The outcome of cerebral ischemic stroke may be affected by its subtype. This may help the clinician to tailor better individual plan of management.




J Neurol Res. 2017;7(4-5):80-84
doi: https://doi.org/10.14740/jnr450w