Diffuse Astrocytoma and Ollier’s Disease

Abstract

Several syndromes are associated with an increased incidence of intracranial tumors. Among these is enchondromatosis. It is a rare, nonhereditary condition. The common subtypes of enchondromatosis are Ollier’s disease (OD) and Maffucci syndrome. It has been distinguished between them by the presence of vascular malformation and non-skeletal neoplasm in Maffucci syndrome. The emergence of malignant neoplasms, including gliomas is a well-recognized complication in Maffucci syndrome, but over the past few years there has been an increasing number of reported cases of patients with intracranial tumors and OD. In our case report we discuss a 23-year-old female recently diagnosed with World Health Organization (WHO) grade II diffuse astrocytoma and found to have OD.

J Neurol Res. 2020;10(6):240-244
doi: https://doi.org/10.14740/jnr580